Evidence Passport
Cryo-EM and an AI-designed scaffold show how Andes hantavirus binds cells
Top story 3 in the issue of 23 October 2026, in 32 AI Biotechnology.
Original source
Cryo-EM and an AI-designed scaffold show how Andes hantavirus binds cells
Reporting a Nature paper, teams at Albert Einstein College of Medicine, Institut Pasteur and LSU Health Shreveport resolved how the virus spike grips the human receptor PCDH1, and how antibodies block it.
Evidence
Evidence: Peer-reviewed (evidence step 5 of 6)
Published after review by independent experts.
The story in three lines
- Key finding
- Near-atomic structures show how the Andes virus spike captures the human PCDH1 receptor and how antibodies interfere.
- Significance
- Clinical: Andes virus can spread between people, so knowing its entry step points to targets for treatments.
- Takeaway
- Laboratory structural work; any drug or vaccine based on it is still years away.
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